Lehrstuhl für Biotechnologie und Biophysik

    Prof. Dr. Markus Sauer

    Telefon:
    E-Mail:
    Sekretariat:
    Telefon:
    Fax:

    +49 931 31-88687
    m.sauer@uni-wuerzburg.de
    Astrid Thal
    +49 931 31-84507
    +49 931 31-84509

    Editorial boards
    2015-presentHistochemistry and Cell Biology
    2014-presentJournal of Structural Biology
    2012-presentMethods in Applications in Fluorescence
    2011-presentPLoS ONE

    List of publications

    [2017] [2016] [2015] [2014] [2013] [2012] [2011] [2010] [2009] [2008] [2007] [2006] [2005] [2004] [2003] [2002] [2001] [2000] [1999] [1998] [1997] [1996] [1995] [1994] [1993]

    2017 [ nach oben ]

    • Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A., Sauer, M.: Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy. Angewandte Chemie. (2017).
       
    • Memmel, S., Sisario, D., Zöller, C., Fiedler, V., Katzer, A., Heiden, R., Becker, N., Eing, L., Ferreira, F.L.R., Zimmermann, H., Sauer, M., Flentje, M., Sukhorukov, V.L., Djuzenova, C.S.: Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities. Oncotarget. Advance Publications, (2017).
       
    • Sauer, M., Heilemann, M.: Single-Molecule Localization Microscopy in Eukaryotes. Chem. Rev. (2017).
       

    2016 [ nach oben ]

    • Franke, C., Sauer, M., van de Linde, S.: Photometry unlocks 3D information from 2D localization microscopy data. Nat Meth. advance online publication, (2016).
       
    • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Stromgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Nat Chem Biol. advance online publication, (2016).
       
    • Mateos-Gil, P., Letschert, S., Doose, S., Sauer, M.: Super-resolution imaging of plasma membrane proteins with click chemistry. Frontiers in Cell and Developmental Biology. 4, 98-- (2016).
       
    • Collenburg, L., Walter, T., Burgert, A., Müller, N., Seibel, J., Japtok, L., Kleuser, B., Sauer, M., Schneider-Schaulies, S.: A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells. The Journal of Immunology. 196, 3951--3962 (2016).
       
    • Dugar, G., Svensson, S.L., Bischler, T., Wäldchen, S., Reinhardt, R., Sauer, M., Sharma, C.M.: The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. Nature Communications. 7, 11667-- (2016).
       
    • Niehorster, T., Loschberger, A., Gregor, I., Kramer, B., Rahn, H.-J., Patting, M., Koberling, F., Enderlein, J., Sauer, M.: Multi-target spectrally resolved fluorescence lifetime imaging microscopy. Nat Meth. advance online publication, (2016).
       
    • Markert, S.M., Britz, S., Proppert, S., Lang, M., Witvliet, D., Mulcahy, B., Sauer, M., Zhen, M., Bessereau, J.-L., Stigloher, C.: Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome. Neurophotonics. 3, 041802--041802 (2016).
       
    • Yadav, P., Selvaraj, B.T., Bender, F.L.P., Behringer, M., Moradi, M., Sivadasan, R., Dombert, B., Blum, R., Asan, E., Sauer, M., Julien, J.-P., Sendtner, M.: Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. 132, 93--110 (2016).
       

    2015 [ nach oben ]

    • Burgert, A., Letschert, S., Doose, S., Sauer, M.: Artifacts in single-molecule localization microscopy. Histochemistry and Cell Biology. 144, 123-131 (2015).
       
    • Schücker, K., Holm, T., Franke, C., Sauer, M., Benavente, R.: Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution. Proceedings of the National Academy of Sciences. 112, 2029-2033 (2015).
       
    • Ehmann, N., Sauer, M., Kittel, R.J.: Super-resolution microscopy of the synaptic active zone. Frontiers in Cellular Neuroscience. 9, (2015).
       
    • Hennig, S., van de Linde, S., Lummer, M., Simonis, M., Huser, T., Sauer, M.: Instant Live-Cell Super-Resolution Imaging of Cellular Structures by Nanoinjection of Fluorescent Probes. Nano Lett. 15, 1374--1381 (2015).
       
    • Schneider, J., Klein, T., Mielich-Süss, B., Koch, G., Franke, C., Kuipers, O.P., Kovács, Á.T., Sauer, M., Lopez, D.: Spatio-temporal Remodeling of Functional Membrane Microdomains Organizes the Signaling Networks of a Bacterium. PLoS Genet. 11, e1005140-- (2015).
       
    • Paul, M.M., Pauli, M., Ehmann, N., Hallermann, S., Sauer, M., Kittel, R.J., Heckmann, M.: Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation. Frontiers in Cellular Neuroscience. 9, (2015).
       
    • Andronic, J., Shirakashi, R., Pickel, S.U., Westerling, K.M., Klein, T., Holm, T., Sauer, M., Sukhorukov, V.L.: Hypotonic Activation of the Myo-Inositol Transporter SLC5A3 in HEK293 Cells Probed by Cell Volumetry, Confocal and Super-Resolution Microscopy. PLoS ONE. 10, e0119990 (2015).
       
    • Wäldchen, S., Lehmann, J., Klein, T., van de Linde, S., Sauer, M.: Light-induced cell damage in live-cell super-resolution microscopy. Scientific Reports. 5, 15348-- (2015).
       
    • Grimm, J.B., Klein, T., Kopek, B.G., Shtengel, G., Hess, H.F., Sauer, M., Lavis, L.D.: Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy. Angewandte Chemie. n/a--n/a (2015).
       
    • von Eyss, B., Jaenicke, L. A., Kortlever, R. M., Royla, N., Wiese, K. E., Letschert, S., McDuffus, L.-A., Sauer, M., Rosenwald, A., Evan, G. I., Kempa, S., Eilers, M.: A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer. Cancer Cell. 28, 743--757 (2015).
       
    • Hennig, S., van de Linde, S., Bergmann, S., Huser, T., Sauer, M.: Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns. ACS Nano. 9, 8122--8130 (2015).
       
    • Werner, C., Pauli, M., Doose, S., Weishaupt, A., Haselmann, H., Grünewald, B., Sauer, M., Heckmann, M., Toyka, K.V., Asan, E., Sommer, C., Geis, C.: Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition. Brain. (2015).
       

    2014 [ nach oben ]

    • Löschberger, A., Franke, C., Krohne, G., van de Linde, S., Sauer, M.: Correlative super-resolution fluorescence and electron microscopy of the nuclear pore complex with molecular resolution. Journal of Cell Science. 127, 4351-4355 (2014).
       
    • Ehmann, N., van de Linde, S., Alon, A., Ljaschenko, D., Keung, X.Z., Holm, T., Rings, A., DiAntonio, A., Hallermann, S., Ashery, U., Heckmann, M., Sauer, M., Kittel, R.J.: Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states. Nat Commun. 5, (2014).
       
    • Letschert, S., Göhler, A., Franke, C., Bertleff-Zieschang, N., Memmel, E., Doose, S., Seibel, J., Sauer, M.: Super-Resolution Imaging of Plasma Membrane Glycans. Angewandte Chemie International Edition. n/a--n/a (2014).
       
    • Mehlitz, A., Karunakaran, K., Herweg, J.-A., Krohne, G., van de Linde, S., Rieck, E., Sauer, M., Rudel, T.: The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. Cellular Microbiology. n/a--n/a (2014).
       
    • Proppert, S., Wolter, S., Holm, T., Klein, T., van de Linde, S., Sauer, M.: Cubic B-spline calibration for 3D super-resolution measurements using astigmatic imaging. Opt. Express. 22, 10304--10316 (2014).
       
    • Andreska, T., Aufmkolk, S., Sauer, M., Blum, R.: High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Frontiers in Cellular Neuroscience. 8, (2014).
       
    • Löschberger, A., Niehörster, T., Sauer, M.: Click chemistry for the conservation of cellular structures and fluorescent proteins: ClickOx. Biotechnology Journal. n/a--n/a (2014).
       
    • Holm, T., Klein, T., Löschberger, A., Klamp, T., Wiebusch, G., van de Linde, S., Sauer, M.: A Blueprint for Cost-Efficient Localization Microscopy. ChemPhysChem. 15, 651--654 (2014).
       
    • Sauer, M., Neuweiler, H.: PET-FCS: Probing Rapid Structural Fluctuations of Proteins and Nucleic Acids by Single-Molecule Fluorescence Quenching. In: Engelborghs, Y. und Visser, A.J.W.G. (hrsg.) Methods Mol Biol - Fluorescence Spectroscopy and Microscopy. S. 597-615. Humana Press (2014).
       
    • van de Linde, S., Sauer, M.: How to switch a fluorophore: from undesired blinking to controlled photoswitching. Chem. Soc. Rev. 2014. 43(4), 1076-1087 (2014).
       
    • Whelan, D.R., Holm, T., Sauer, M., Bell, T.D.M.: Focus on Super-Resolution Imaging with Direct Stochastic Optical Reconstruction Microscopy (dSTORM). Australian Journal of Chemistry. 67, 179-183 (2014).
       

    2013 [ nach oben ]

    • Andronic, J., Bobak, N., Bittner, S., Ehling, P., Kleinschnitz, C., Herrmann, A.M., Zimmermann, H., Sauer, M., Wiendl, H., Budde, T., Meuth, S.G., Sukhorukov, V.L.: Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828, 699 - 707 (2013).
       
    • Klamp, T., Camps, M., Nieto, B., Guasch, F., Ranasinghe, R.T., Wiedemann, J., Petrášek, Z., Schwille, P., Klenerman, D., Sauer, M.: Highly Rapid Amplification-Free and Quantitative DNA Imaging Assay. Sci. Rep. 3, (2013).
       
    • Sauer, M.: Localization microscopy coming of age: from concepts to biological impact. Journal of Cell Science. 126, 3505-3513 (2013).
       
    • Kolesinska, B., Podwysocka, D.J., Rueping, M.A., Seebach, D., Kamena, F., Walde, P., Sauer, M., Windschiegl, B., Meyer-Ács, M., Vor der Brüggen, M., Giehring, S.: Permeation through Phospholipid Bilayers, Skin-Cell Penetration, Plasma Stability, and CD Spectra of α- and β-Oligoproline Derivatives. Chemistry & Biodiversity. 10, 1--38 (2013).
       
    • van de Linde, S., Aufmkolk, S., Franke, C., Holm, T., Klein, T., Löschberger, A., Proppert, S., Wolter, S., Sauer, M.: Investigating Cellular Structures at the Nanoscale with Organic Fluorophores. Chemistry & Biology. 20, 8 - 18 (2013).
       
    • Seibel, J., König, S., Göhler, A., Doose, S., Memmel, E., Bertleff, N., Sauer, M.: Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics. Expert Rev Proteomics. 10, 25--31 (2013).
       
    • Schäfer, P., van de Linde, S., Lehmann, J., Sauer, M., Doose, S.: Methylene blue- and thiol-based oxygen depletion for super-resolution imaging. Analytical Chemistry. 85, 3393 - 3400 (2013).
       

    2012 [ nach oben ]

    • Yahiatène, I., Doose, S., Huser, T., Sauer, M.: Correlation-Matrix Analysis of Two-Color Coincidence Events in Single-Molecule Fluorescence Experiments. Analytical Chemistry. 84, 2729-2736 (2012).
       
    • Wolter, S., Loschberger, A., Holm, T., Aufmkolk, S., Dabauvalle, M.-C., van de Linde, S., Sauer, M.: rapidSTORM: accurate, fast open-source software for localization microscopy. Nat Meth. 9, 1040--1041 (2012).
       
    • Lando, D., Endesfelder, U., Berger, H., Subramanian, L., Dunne, P.D., McColl, J., Klenerman, D., Carr, A.M., Sauer, M., Allshire, R.C., Heilemann, M., Laue, E.D.: Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast. Open Biology. 2, (2012).
       
    • Klein, T., van de Linde, S., Sauer, M.: Live-Cell Super-Resolution Imaging Goes Multicolor. ChemBioChem. 13, 1861--1863 (2012).
       
    • Terpitz, U., Letschert, S., Bonda, U., Spahn, C., Guan, C., Sauer, M., Zimmermann, U., Bamberg, E., Zimmermann, D., Sukhorukov, V.: Dielectric Analysis and Multi-cell Electrofusion of the Yeast Pichia pastoris for Electrophysiological Studies. Journal of Membrane Biology. 1-12 (2012).
       
    • van de Linde, S., Heilemann, M., Sauer, M.: Live-Cell Super-Resolution Imaging with Synthetic Fluorophores. Annual Review of Physical Chemistry. 63, null (2012).
       
    • Owen, D.M., Sauer, M., Gaus, K.: Fluorescence localization microscopy: The transition from concept to biological research tool. cib. 5, 0---1 (2012).
       
    • Löschberger, A., van de Linde, S., Dabauvalle, M.-C., Rieger, B., Heilemann, M., Krohne, G., Sauer, M.: Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution. Journal of Cell Science. 125, 570-575 (2012).
       
    • Dertinger, T., Colyer, R., Vogel, R., Heilemann, M., Sauer, M., Enderlein, J., Weiss, S.: Superresolution Optical Fluctuation Imaging (SOFI). Advances in Experimental Medicine and Biology. 733, 17-21 (2012).
       
    • WOLTER, S., SAUER, M.: Follow-up to paper by S. Wolter, M. Schüttpelz, M. Tscherepanow, S. van de Linde, M. Heilemann and M. Sauer, entitled Real-Time Computation of Subdiffraction-Resolution Fluorescence Images. Journal of Microscopy. 245, 109--109 (2012).
       
    • Bar-On, D., Wolter, S., van de Linde, S., Heilemann, M., Nudelman, G., Nachliel, E., Gutman, M., Sauer, M., Ashery, U.: Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters. Journal of Biological Chemistry. (2012).
       

    2011 [ nach oben ]

    • Vogel, B., Löschberger, A., Sauer, M., Hock, R.: Cross-linking of DNA through HMGA1 suggests a DNA scaffold. Nucleic Acids Research. (2011).
       
    • Kaminski Schierle, G.S., van de Linde, S., Erdelyi, M., Esbjörner, E.K., Klein, T., Rees, E., Bertoncini, C.W., Dobson, C.M., Sauer, M., Kaminski, C.F.: In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging. Journal of the American Chemical Society. 133, 12902-12905 (2011).
       
    • van de Linde, S., Wolter, S., Sauer, M.: Single-molecule Photoswitching and Localization. Aust. J. Chem. 64, 503--511 (2011).
       
    • Bollmann, S., Lollmann, M., Sauer, M., Doose, S.: Dimer formation of organic fluorophores reports on biomolecular dynamics under denaturing conditions. Phys. Chem. Chem. Phys. 13, 12874-12882 (2011).
       
    • Bollmann, S., Burgert, A., Plattner, C., Nagel, L., Sewald, N., Löllmann, M., Sauer, M., Doose, S.: Conformational Flexibility of Glycosylated Peptides. ChemPhysChem. 12, 2907--2911 (2011).
       
    • van de Linde, S., Krstic, I., Prisner, T., Doose, S., Heilemann, M., Sauer, M.: Photoinduced formation of reversible dye radicals and their impact on super-resolution imaging. Photochem. Photobiol. Sci. 10, 499-506 (2011).
       
    • Wolter, S., Endesfelder, U., van de Linde, S., Heilemann, M., Sauer, M.: Measuring localization performance of super-resolution algorithms on very active samples. Optics Express. 19, 7020--33 (2011).
       
    • van de Linde, S., Loschberger, A., Klein, T., Heidbreder, M., Wolter, S., Heilemann, M., Sauer, M.: Direct stochastic optical reconstruction microscopy with standard fluorescent probes. Nat. Protocols. 6, 991--1009 (2011).
       
    • Noe, F., Doose, S., Daidone, I., Löllmann, M., Sauer, M., Chodera, J.D., Smith, J.C.: Dynamical fingerprints for probing individual relaxation processes in biomolecular dynamics with simulations and kinetic experiments. Proceedings of the National Academy of Sciences. (2011).
       
    • Klein, T., Loeschberger, A., Proppert, S., Wolter, S., van de Linde, S., Sauer, M.: Live-cell dSTORM with SNAP-tag fusion proteins. NATURE METHODS. 8, 7-9 (2011).
       

    2010 [ nach oben ]

    • Endesfelder, U., van de Linde, S., Wolter, S., Sauer, M., Heilemann, M.: Subdiffraction-Resolution Fluorescence Microscopy of Myosin-Actin Motility. CHEMPHYSCHEM. 11, 836-840 (2010).
       
    • Dertinger, T., Heilemann, M., Vogel, R., Sauer, M., Weiss, S.: Superresolution Optical Fluctuation Imaging with Organic Dyes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 49, 9441-9443 (2010).
       
    • Daidone, I., Neuweiler, H., Doose, S., Sauer, M., Smith, J.C.: Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains. PLOS COMPUTATIONAL BIOLOGY. 6, (2010).
       
    • Kasper, R., Harke, B., Forthmann, C., Tinnefeld, P., Hell, S.W., Sauer, M.: Single-Molecule STED Microscopy with Photostable Organic Fluorophores. Small. 6, 1379--1384 (2010).
       
    • Goehler, A., Andre, S., Kaltner, H., Sauer, M., Gabius, H.-J., Doose, S.: Hydrodynamic Properties of Human Adhesion/Growth-Regulatory Galectins Studied by Fluorescence Correlation Spectroscopy. BIOPHYSICAL JOURNAL. 98, 3044-3053 (2010).
       
    • Nottbohm, C.T., Sopher, R., Heilemann, M., Sauer, M., Goelzhaeuser, A.: Fluorescently labeled 1 nm thin nanomembranes. JOURNAL OF BIOTECHNOLOGY. 149, 267-271 (2010).
       
    • Schlereth, K., Beinoraviciute-Kellner, R., Zeitlinger, M.K., Bretz, A.C., Sauer, M., Charles, J.P., Vogiatzi, F., Leich, E., Samans, B., Eilers, M., Kisker, C., Rosenwald, A., Stiewe, T.: DNA Binding Cooperativity of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis. MOLECULAR CELL. 38, 356-368 (2010).
       
    • Zheng, Z., Nottbohm, C.T., Turchanin, A., Muzik, H., Beyer, A., Heilemann, M., Sauer, M., Goelzhaeuser, A.: Janus Nanomembranes: A Generic Platform for Chemistry in Two Dimensions. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 49, 8493-8497 (2010).
       
    • Seefeldt, B., Kasper, R., Beining, M., Mattay, J., Arden-Jacob, J., Kemnitzer, N., Drexhage, K.H., Heilemann, M., Sauer, M.: Spiropyrans as molecular optical switches. PHOTOCHEMICAL \& PHOTOBIOLOGICAL SCIENCES. 9, 213-220 (2010).
       
    • Goelzhaeuser, A., Nattkemper, T., Niehaus, K., Puehler, A., Sauer, M.: BioImaging: Contributions from biology, physics and informatics. JOURNAL OF BIOTECHNOLOGY. 149, 227-228 (2010).
       
    • Seidel, T., Seefeldt, B., Sauer, M., Dietz, K.-J.: In vivo analysis of the 2-Cys peroxiredoxin oligomeric state by two-step FRET. JOURNAL OF BIOTECHNOLOGY. 149, 272-279 (2010).
       
    • Wombacher, R., Heidbreder, M., van de Linde, S., Sheetz, M.P., Heilemann, M., Cornish, V.W., Sauer, M.: Live-cell super-resolution imaging with trimethoprim conjugates. NATURE METHODS. 7, 717-U72 (2010).
       
    • Wolter, S., Schuettpelz, M., Tscherepanow, M., van de Linde, S., Heilemann, M., Sauer, M.: Real-time computation of subdiffraction-resolution fluorescence images. JOURNAL OF MICROSCOPY-OXFORD. 237, 12-22 (2010).
       
    • Kottke, T., van de Linde, S., Sauer, M., Kakorin, S., Heilemann, M.: Identification of the Product of Photoswitching of an Oxazine Fluorophore Using Fourier Transform Infrared Difference Spectroscopy. The Journal of Physical Chemistry Letters. 1, 3156-3159 (2010).
       
    • van de Linde, S., Wolter, S., Heilemann, M., Sauer, M.: The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging. JOURNAL OF BIOTECHNOLOGY. 149, 260-266 (2010).
       

    2009 [ nach oben ]

    • Hennig, S., van de Linde, S., Heilemann, M., Sauer, M.: Quantum Dot Triexciton Imaging with Three-Dimensional Subdiffraction Resolution. NANO LETTERS. 9, 2466-2470 (2009).
       
    • Doose, S., Neuweiler, H., Sauer, M.: Fluorescence Quenching by Photoinduced Electron Transfer: A Reporter for Conformational Dynamics of Macromolecules. CHEMPHYSCHEM. 10, 1389-1398 (2009).
       
    • Heilemann, M., van de Linde, S., Mukherjee, A., Sauer, M.: Super-Resolution Imaging with Small Organic Fluorophores. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 48, 6903-6908 (2009).
       
    • van de Linde, S., Endesfelder, U., Mukherjee, A., Schuettpelz, M., Wiebusch, G., Wolter, S., Heilemann, M., Sauer, M.: Multicolor photoswitching microscopy for subdiffraction-resolution fluorescence imaging. PHOTOCHEMICAL \& PHOTOBIOLOGICAL SCIENCES. 8, 465-469 (2009).
       
    • Heilemann, M., Dedecker, P., Hofkens, J., Sauer, M.: Photoswitches: Key molecules for subdiffraction-resolution fluorescence imaging and molecular quantification. LASER \& PHOTONICS REVIEWS. 3, 180-202 (2009).
       

    2008 [ nach oben ]

    • Seefeldt, B., Kasper, R., Seidel, T., Tinnefeld, P., Dietz, K.-J., Heilemann, M., Sauer, M.: Fluorescent proteins for single-molecule fluorescence applications. JOURNAL OF BIOPHOTONICS. 1, 74-82 (2008).
       
    • van de Linde, S., Sauer, M., Heilemann, M.: Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores. JOURNAL OF STRUCTURAL BIOLOGY. 164, 250-254 (2008).
       
    • Vogelsang, J., Kasper, R., Steinhauer, C., Person, B., Heilemann, M., Sauer, M., Tinnefeld, P.: A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 47, 5465-5469 (2008).
       
    • van de Linde, S., Kasper, R., Heilemann, M., Sauer, M.: Photoswitching microscopy with standard fluorophores. APPLIED PHYSICS B-LASERS AND OPTICS. 93, 725-731 (2008).
       
    • Seidel, T., Schnitzer, D., Golldack, D., Sauer, M., Dietz, K.-J.: Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis. BMC CELL BIOLOGY. 9, (2008).
       
    • Heilemann, M., van de Linde, S., Schuttpelz, M., Kasper, R., Seefeldt, B., Mukherjee, A., Tinnefeld, P., Sauer, M.: Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 47, 6172-6176 (2008).
       
    • Schuettpelz, M., Schoening, J.C., Doose, S., Neuweiler, H., Peters, E., Staiger, D., Sauer, M.: Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 130, 9507-9513 (2008).
       

    2007 [ nach oben ]

    • Doose, S., Barsch, H., Sauer, M.: Polymer properties of polythymine as revealed by translational diffusion. BIOPHYSICAL JOURNAL. 93, 1224-1234 (2007).
       
    • Schulze, P., Schuettpelz, M., Sauer, M., Belder, D.: Two-photon excited fluorescence detection at 420 nm for label-free detection of small aromatics and proteins in microchip electrophoresis. LAB ON A CHIP. 7, 1841-1844 (2007).
       
    • Doose, S., Neuweiler, H., Barsch, H., Sauer, M.: Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 104, 17400-17405 (2007).
       
    • Vogelsang, J., Doose, S., Sauer, M., Tinnefeld, P.: Single-Molecule Fluorescence Resonance Energy Transfer in Nanopipets: Improving Distance Resolution and Concentration Range. ANALYTICAL CHEMISTRY. 79, 7367-7375 (2007).
       
    • Neuweiler, H., Lollmann, M., Doose, S., Sauer, M.: Dynamics of unfolded polypeptide chains in crowded environment studied by fluorescence correlation spectroscopy. JOURNAL OF MOLECULAR BIOLOGY. 365, 856-869 (2007).
       
    • Clifford, J.N., Bell, T.D.M., Tinnefeld, P., Heilemann, M., Melnikov, S.M., ichi Hotta, J., Sliwa, M., Dedecker, P., Sauer, M., Hofkens, J., Yeow, E.K.L.: Fluorescence of single molecules in polymer films: Sensitivity of blinking to local environment. JOURNAL OF PHYSICAL CHEMISTRY B. 111, 6987-6991 (2007).
       
    • Agaylan, A., Binder, D., Sauer, M., Neuweiler, H., Meyer, O., Kiesewetter, H., Salama, A.: A highly sensitive particle agglutination assay for the detection of P53 autoantibodies in patients with lung cancer. Cancer. 110, 2502--2506 (2007).
       

    2006 [ nach oben ]

    • Kurtz, R., Fricke, M., Kalb, J., Tinnefeld, P., Sauer, M.: Application of multiline two-photon microscopy to functional in vivo imaging. JOURNAL OF NEUROSCIENCE METHODS. 151, 276-286 (2006).
       
    • Biebricher, A., Sauer, M., Tinnefeld, P.: Radiative and nonradiative rate fluctuations of single colloidal semiconductor nanocrystals. JOURNAL OF PHYSICAL CHEMISTRY B. 110, 5174-5178 (2006).
       
    • Kim, J., Doose, S., Neuweiler, H., Sauer, M.: The initial step of DNA hairpin folding: a kinetic analysis using fluorescence correlation spectroscopy. NUCLEIC ACIDS RESEARCH. 34, 2516-2527 (2006).
       
    • Schüttpelz, M., Müller, C., Neuweiler, H., Sauer, M.: UV Fluorescence Lifetime Imaging Microscopy: A Label-Free Method for Detection and Quantification of Protein Interactions. Analytical Chemistry. 78, 663-669 (2006).
       
    • Sanchez-Mosteiro, G., van Dijk, E.M.H.P., Hernando, J., Heilemann, M., Tinnefeld, P., Sauer, M., Koberlin, F., Patting, M., Wahl, M., Erdmann, R., van Hulst, N.F., Garcia-Parajo, M.F.: DNA-based molecular wires: Multiple emission pathways of individual constructs. JOURNAL OF PHYSICAL CHEMISTRY B. 110, 26349-26353 (2006).
       
    • Heilemann, M., Kasper, R., Tinnefeld, P., Sauer, M.: Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-Based photonic wires. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 128, 16864-16875 (2006).
       
    • Marmé, N., Friedrich, A., Müller, M., Nolte, O., Wolfrum, J., Hoheisel, J.D., Sauer, M., Knemeyer, J.-P.: Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy. Nucl. Acids Res. 34, e90 (2006).
       
    • Cam, H., Griesmann, H., Beitzinger, M., Hofmann, L., Beinoraviciute-Kellner, R., Sauer, M., Huettinger-Kirchhof, N., Oswald, C., Friedl, P., Gattenloehner, S., Burek, C., Rosenwald, A., Stiewe, T.: p53 family members in myogenic differentiation and rhabdomyosarcoma development. CANCER CELL. 10, 281-293 (2006).
       

    2005 [ nach oben ]

    • Heilemann, M., Margeat, E., Kasper, R., Sauer, M., Tinnefeld, P.: Carbocyanine dyes as efficient reversible single-molecule optical switch. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 127, 3801-3806 (2005).
       
    • Tinnefeld, P., Sauer, M.: Branching Out of Single-Molecule Fluorescence Spectroscopy: Challenges for Chemistry and Influence on Biology. Angewandte Chemie International Edition. 44, 2642--2671 (2005).
       
    • Patra, D., Gregor, I., Enderlein, J., Sauer, M.: Defocused imaging of quantum-dot angular distribution of radiation. APPLIED PHYSICS LETTERS. 87, (2005).
       
    • Stohr, K., Hafner, B., Nolte, O., Wolfrum, J., Sauer, M., Herten, D.P.: Species-specific identification of mycobacterial 16S rRNA PCR amplicons using smart probes. ANALYTICAL CHEMISTRY. 77, 7195-7203 (2005).
       
    • Doose, S., Neuweiler, H., Sauer, M.: A close look at fluorescence quenching of organic dyes by tryptophan. CHEMPHYSCHEM. 6, 2277-2285 (2005).
       
    • Neuweiler, H., Doose, S., Sauer, M.: A microscopic view of miniprotein folding: Enhanced folding efficiency through formation of an intermediate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 102, 16650-16655 (2005).
       
    • Tinnefeld, P., Heilemann, M., Sauer, M.: Design of molecular photonic wires based on multistep electronic excitation transfer. CHEMPHYSCHEM. 6, 217-222 (2005).
       
    • Knemeyer, J.P., Marme, N., Hafner, B., Habl, G., Schafer, G., Muller, M., Nolte, O., Sauer, M., Wolfrum, J.: Self-quenching DNA probes based on dye dimerization for identification of mycobacteria. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY. 85, 625-637 (2005).
       
    • Heinlein, T., Biebricher, A., Schluter, P., Roth, C.M., Herten, D.P., Wolfrum, J., Heilemann, M., Muller, C., Tinnefeld, P., Sauer, M.: High-resolution colocalization of single molecules within the resolution gap of far-field microscopy. CHEMPHYSCHEM. 6, 949-955 (2005).
       
    • Scheffler, S., Sauer, M., Neuweiler, H.: Monitoring antibody binding events in homogeneous solution by single-molecule fluorescence spectroscopy. ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY \& CHEMICAL PHYSICS. 219, 665-678 (2005).
       
    • Sauer, M.: Reversible molecular photoswitches: A key technology for nanoscience and fluorescence imaging. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 102, 9433-9434 (2005).
       
    • Neuweiler, H., Sauer, M.: Exploring life by single-molecule fluorescence spectroscopy. ANALYTICAL CHEMISTRY. 77, 178A-185A (2005).