Dr. Hannes Neuweiler

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Dr. Hannes Neuweiler
Telefon:
E-Mail:
+49 931 31-83872
hannes.neuweiler@uni-wuerzburg.de

List of publications

[2016] [2015] [2014] [2013] [2012] [2011] [2010] [2009] [2008] [2007] [2006] [2005] [2004] [2003] [2002]

2016 [ nach oben ]

  • Schulze, A., Beliu, G., Helmerich, D.A., Schubert, J., Pearl, L.H., Prodromou, C., Neuweiler, H.: Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism. Nat Chem Biol. advance online publication, (2016).
     

2015 [ nach oben ]

  • Thukral, L., Schwarze, S., Daidone, I., Neuweiler, H.: β-Structure within the Denatured State of the Helical Protein Domain BBL. Journal of Molecular Biology. (2015).
     

2014 [ nach oben ]

  • Ries, J., Schwarze, S., Johnson, C.M., Neuweiler, H.: Microsecond folding and domain motions of a spider silk protein structural switch. Journal of the American Chemical Society. null (2014).
     
  • Sauer, M., Neuweiler, H.: PET-FCS: Probing Rapid Structural Fluctuations of Proteins and Nucleic Acids by Single-Molecule Fluorescence Quenching. In: Engelborghs, Y. and Visser, A.J.W.G. (eds.) Methods Mol Biol - Fluorescence Spectroscopy and Microscopy. pp. 597-615. Humana Press (2014).
     

2013 [ nach oben ]

  • Schwarze, S., Zwettler, F.U., Johnson, C.M., Neuweiler, H.: The N-terminal domains of spider silk proteins assemble ultrafast and protected from charge screening. Nat Commun. 4, (2013).
     

2012 [ nach oben ]

  • Lum, J.K., Neuweiler, H., Fersht, A.R.: Long-Range Modulation of Chain Motions within the Intrinsically Disordered Transactivation Domain of Tumor Suppressor p53. Journal of the American Chemical Society. 134, 1617-1622 (2012).
     

2011 [ nach oben ]

  • Jensen, M.H., Sukumaran, M., Johnson, C.M., Greger, I.H., Neuweiler, H.: Intrinsic Motions in the N-Terminal Domain of an Ionotropic Glutamate Receptor Detected by Fluorescence Correlation Spectroscopy. Journal of Molecular Biology. 414, 96 - 105 (2011).
     
  • Teufel, D.P., Johnson, C.M., Lum, J.K., Neuweiler, H.: Backbone-Driven Collapse in Unfolded Protein Chains. Journal of Molecular Biology. 409, 250 - 262 (2011).
     

2010 [ nach oben ]

  • Neuweiler, H., Banachewicz, W., Fersht, A.R.: Kinetics of chain motions within a protein-folding intermediate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107, 22106-22110 (2010).
     
  • Daidone, I., Neuweiler, H., Doose, S., Sauer, M., Smith, J.C.: Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains. PLOS COMPUTATIONAL BIOLOGY. 6, (2010).
     
  • Arbely, E., Neuweiler, H., Sharpe, T.D., Johnson, C.M., Fersht, A.R.: The human peripheral subunit-binding domain folds rapidly while overcoming repulsive Coulomb forces. PROTEIN SCIENCE. 19, 1704-1713 (2010).
     
  • Arbely, E., Rutherford, T.J., Neuweiler, H., Sharpe, T.D., Ferguson, N., Fersht, A.R.: Carboxyl pK(a) Values and Acid Denaturation of BBL. JOURNAL OF MOLECULAR BIOLOGY. 403, 313-327 (2010).
     

2009 [ nach oben ]

  • Neuweiler, H., Sharpe, T.D., Johnson, C.M., Teufel, D.P., Ferguson, N., Fersht, A.R.: Downhill versus Barrier-Limited Folding of BBL 2: Mechanistic Insights from Kinetics of Folding Monitored by Independent Tryptophan Probes. JOURNAL OF MOLECULAR BIOLOGY. 387, 975-985 (2009).
     
  • Neuweiler, H., Johnson, C.M., Fersht, A.R.: Direct observation of ultrafast folding and denatured state dynamics in single protein molecules. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106, 18569-18574 (2009).
     
  • Neuweiler, H., Sharpe, T.D., Rutherford, T.J., Johnson, C.M., Allen, M.D., Ferguson, N., Fersht, A.R.: The Folding Mechanism of BBL: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family. JOURNAL OF MOLECULAR BIOLOGY. 390, 1060-1073 (2009).
     
  • Huang, F., Ying, L., Neuweiler, H., Fersht, A.R.: Reply to Campos et al.: Direct observation versus ambiguous kinetics and thermodynamics. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106, E140 (2009).
     
  • Doose, S., Neuweiler, H., Sauer, M.: Fluorescence Quenching by Photoinduced Electron Transfer: A Reporter for Conformational Dynamics of Macromolecules. CHEMPHYSCHEM. 10, 1389-1398 (2009).
     

2008 [ nach oben ]

  • Schuettpelz, M., Schoening, J.C., Doose, S., Neuweiler, H., Peters, E., Staiger, D., Sauer, M.: Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 130, 9507-9513 (2008).
     

2007 [ nach oben ]

  • Neuweiler, H., Lollmann, M., Doose, S., Sauer, M.: Dynamics of unfolded polypeptide chains in crowded environment studied by fluorescence correlation spectroscopy. JOURNAL OF MOLECULAR BIOLOGY. 365, 856-869 (2007).
     
  • Agaylan, A., Binder, D., Sauer, M., Neuweiler, H., Meyer, O., Kiesewetter, H., Salama, A.: A highly sensitive particle agglutination assay for the detection of P53 autoantibodies in patients with lung cancer. Cancer. 110, 2502--2506 (2007).
     
  • Doose, S., Neuweiler, H., Barsch, H., Sauer, M.: Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 104, 17400-17405 (2007).
     

2006 [ nach oben ]

  • Kim, J., Doose, S., Neuweiler, H., Sauer, M.: The initial step of DNA hairpin folding: a kinetic analysis using fluorescence correlation spectroscopy. NUCLEIC ACIDS RESEARCH. 34, 2516-2527 (2006).
     
  • Schüttpelz, M., Müller, C., Neuweiler, H., Sauer, M.: UV Fluorescence Lifetime Imaging Microscopy: A Label-Free Method for Detection and Quantification of Protein Interactions. Analytical Chemistry. 78, 663-669 (2006).
     

2005 [ nach oben ]

  • Scheffler, S., Sauer, M., Neuweiler, H.: Monitoring antibody binding events in homogeneous solution by single-molecule fluorescence spectroscopy. ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY \& CHEMICAL PHYSICS. 219, 665-678 (2005).
     
  • Doose, S., Neuweiler, H., Sauer, M.: A close look at fluorescence quenching of organic dyes by tryptophan. CHEMPHYSCHEM. 6, 2277-2285 (2005).
     
  • Neuweiler, H., Sauer, M.: Exploring life by single-molecule fluorescence spectroscopy. ANALYTICAL CHEMISTRY. 77, 178A-185A (2005).
     
  • Neuweiler, H., Doose, S., Sauer, M.: A microscopic view of miniprotein folding: Enhanced folding efficiency through formation of an intermediate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 102, 16650-16655 (2005).
     

2004 [ nach oben ]

  • Neuweiler, H., Sauer, M.: Using photoinduced charge transfer reactions to study conformational dynamics of biopolymers at the single-molecule level. CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 5, 285-298 (2004).
     

2003 [ nach oben ]

  • Neuweiler, H., Schulz, A., Bohmer, M., Enderlein, J., Sauer, M.: Measurement of submicrosecond intramolecular contact formation in peptides at the single-molecule level. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 125, 5324-5330 (2003).
     
  • Vaiana, A.C., Neuweiler, H., Schulz, A., Wolfrum, J., Sauer, M., Smith, J.C.: Fluorescence quenching of dyes by tryptophan: Interactions at atomic detail from combination of experiment and computer simulation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 125, 14564-14572 (2003).
     

2002 [ nach oben ]

  • Neuweiler, H., Schulz, A., Vaiana, A.C., Smith, J.C., Kaul, S., Wolfrum, J., Sauer, M.: Detection of Individual p53-Autoantibodies by Using Quenched Peptide-Based Molecular Probes. Angewandte Chemie International Edition. 41, 4769--4773 (2002).